External ointment matrix and preparation method thereof


  • Inventors: XUE GUIJUN
  • Assignees: 薛贵军
  • Publication Date: December 01, 2010
  • Publication Number: CN-101897661-A


The invention relates to an external ointment matrix and a preparation method thereof. The external ointment matrix is characterized by consisting of the following raw materials in part by weight: 900 to 1,100 parts of alseodaphne hainanensis ointment, 90 to 110 parts of medical pressure-sensitive adhesive and 29 to 31 parts of azone. The preparation method comprises the following steps of: respectively putting the alseodaphne hainanensis ointment and the medical pressure-sensitive adhesive in the raw materials into two containers and heating for dissolving at the temperature of between 180 and 200 DEG C; pouring the fully dissolved pressure-sensitive adhesive into the container containing the fully dissolved alseodaphne hainanensis ointment, continuing to heat and stirring continuously, so that the alseodaphne hainanensis ointment and the pressure-sensitive adhesive are dissolved and mixed fully to prepare ointment for later use; continuing to heat the mixed ointment over fire, stopping heating until the temperature in the container reaches between 180 and 220 DEG C for cooling; and adding the azone into the raw materials into the ointment of which the temperature is between 150 and 180 DEG C, stirring fully and uniformly to obtain the ointment matrix. The permeability of medicaments can be promoted due to the selection of the medical pressure-sensitive adhesive made of a high molecular nanometer material, so the external ointment has numerous advantages of the conventional ointment with a hard matrix, enables the ointment matrix to be soft, allows patients to apply conveniently, adaptively and comfortably, and is favorable for absorbing the medicaments by subcutaneous deep tissue.




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